Systemic Inflammatory Vasculitis

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Check whether added everything (+ whatever she added)D
Add from Crash and all
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can hear bruit but no pulse over extremtiies
 
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temperal arteritis (most common), but other artieries of carotid
 
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optic arteritis and blindness
> small lumen, lymphocitis infiltration
 
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MEDIUM vessel
can present with coronary ischemia
prophylactic treatment
 
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coronary, rena, mesenteric angiography
we do not biopsy renal because renal aneurysm
 
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Wegener was a nazi
orbital pseudotumor formation
biopsy of lung, kidney, nasal mucosa
 
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saddle nose deformity ⇒ what other causes?
strawberry gums
 
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wrist drop, foot drop also a feature of other vasculitis
nerve biopsy - vasa vervosa eosinophil infiltration
 
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RENO-pulmonary symdromes = the three above vasculitis
 
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ULNAR Mononeuropathy - dorsal guttering
crescentic glomerulities
 
 
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RASH involving legs and buttocks
 
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chronic urticarial lesions with pain or burning sensation
 
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if both kidneys and lungs affected then goodpasture syndrome
 
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pulmonary haemorrhages
 
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tips of fingers, toes, ear lobes etc
associated with cold weather
cryoglobulins at 4 degrees celsius
SPEP associated with multiple myeloma
RF but not proper RA
 
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cryoglobulin precipitate at four degrees in plasma na dblood picture etc
 
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anemia due to bleeding ot chronic disease
 
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HEP B = Poyarteritis nodusa
Hep C = cryoglobinuria
nasal biopsy in wegener;s
nerve - sural?
2d echo in kawasaki
 
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treat the secondary cause either mimics or actual cause
pre-steroid era so many deaths
steroid sparing for long terms, disease modifying drugs by preference of nephrologist
ANCA associate - plasma exhange, IV immunglobic for kawasaki for coronary involvemenr
biologics in the pipeline
 
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