Multiple Myeloma + CASE

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1. Breakdown of haem malignancies?
2. Protein electrophoresis
3. Pathophysiology?
4. How to detect light chain?
5. How it appears in electroprerosesis
6. Classification of monoclonal gammopathies?
7. How to identify specific light chain?
8. Why immunodeficiency?
9. Short mnemonic
10. Diagnosing MM
11. Management
12. Definition?
13. Importance with bone pathology?
14. Haemotolgical cancers?
15. Incidence?
16. Risk factors? xx
17. Clinical manifestations?
18. Mechanisms of the disease?
19. Investgations for multiple myeloma?
20. Characteristic findings7
21. Diagnosis and criteria for diagnosis? xx
22. Staging of the disease
23. Phases of the idsease?
24. When bad prognosis
25. Goas of therapy?
26. Modalities of treatment?
27. Management of complications?
28. Current status of regime?
 
 
 
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Must ask risk factors in history
Must be in dd in bine pain in elderly with metastatis
Mm cN cause all the pathies..
Impending cord compression... Ask numbness or heaviness while walking.... Chronic constipation.... Bowel movements... Spinal cord compresdopm emergency
Msut ask questions to exclude MM in anemia and back pain
Pasmacutoma solitary lung presentation
Pathophilisphu of renal failure in MM Common question 4 ways... Nsaid induced nephrobwthies 1. nenje jnes 2 proteins cause damage 3 cacium => metastatic calcification 4 amyloid deposition 5 nsaid use etc etc
Hyoercakcemia bisohonars ca damage kidney
No need to know s3ocitic gene. Just need rough idea. Same
No need to know exact blood filmm pics.?
No cure but can control symptoms and prolong survival
No need to remember staging of MM at this point.
No need to remember particular drugs. Just principles..... Of treatment.
CASE:
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