Developmental of the female genital tract

broad ligament is the sheeth of periotnuem that the developing paramesonephric duct has ppulled along

2 cervix 2 utereus ⇒ didelphys

1 cervix 2 uterus ⇒ bicornuate

unicorunate uterus

septate uterus (fundus is intact vs bicorunuate where the fundus is dipped)

mullerian agenesis

Mullerian abnormalaties

Diethylstilbestrol Exposure

normal gonads and normal karyotupe and normal breast....vs gonadal dysgeneisis and ASI

can be associated with two vaginas as well if the latter

arcuate ueterus is usually just a radiological anomaly. a dip in the top.

if the rudimenary horn has endometrium and

if rudimentary horn is not connected then blood can be collected and dusmenohrreha

So this is the anomaly where you can get unilateral dysmenorrhea

but if connected then can even have fertilisation and a cornual pregnancy

mullerian agensis is a rare anomaly

DES was used earlier to prevent aborition and strenghten the pregnancy but wwas terotegenic and abnormalaties seen later

no now threatned miscarriage have to just wait and watch

Abortion vs infertiity?

Septate causes most commonly cause abotrion in the second semester but its one abnormalality thsat can cause abortion in t1

causes recurrent abortion because the spetum is less vascular and fribrous and cannot support a placenta

spetate is most problematic one reason its rare

arcuate cause duhhh but didelphs just 2 uetreus and 2 cervix and can go undetected for years

3d usg is cheaper tho. but MRI is the treatment of choice. Mri > HSG

fundus dipped means bicornuate uterus

those 3 are types of metroplasties

which i a unification operation

that can be done for bicornuate and aslo for septum that fails the spetate lysis answer.

the lap and hyesterocopy can be both diagnostic and therpauetic. can confirm thats its septum and not bcornuate and treat in the same operation without having another

choice depends on the full clinical profile ...in this case because priamry inferitity then hys + lap...if recurrent then better to do mri and 3d us

Development of Sex & XY Females

upregulation of other SOMATIC genes

testis development needs Y genes and upregulation of other genes while ovariain evelopment needs absemce of y genes and upregulation of other genes. if nothing then dysgentic.

external genitlai by default is a female but in testerone exposure it gets male. That is the internal gentialia is dependant on testerone to get male but external genitalia needs 5 dht. So requires 5alpha reductase as well.