Delusional Disorders

Delusional Disorders
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Outline
  • Definition of psychosis
  • Types
  • Delusional disorders
  • Epidemiology
  • Aetiology
  • Associated medical conditions
  • Clinical types
  • Clinical Features
  • Differential diagnosis
  • Course and prognosis
  • Management
Psychosis –
  • Gross impairment in reality testing(‘not in contact’ with reality)
  • Marked disturbance in personality, with impairment in social, interpersonal, occupational functioning.
  • Marked impairment in judgement & absent understanding of current symptoms & behaviour(loss of insight)
  • Presence of characteristic symptoms like delusions & hallucinations.
Types of non-organic psychosis
  • Delusional disorders
  • Acute & Transient psychotic disorders
  • Schizoaffective disorders
  • Postpartum psychosis
Delusional Disorders
  • A group of disorders where long standing, non-bizarre delusions are the primary or only manifestation of the illness
  • Included in ICD-10
  • Must be persistent for atleast 3 months.
Epidemiology
  • Prevalence rate- 0.24%-0.3%
  • Late middle age
  • Female:Male – 3:1
  • More common among relatives of Schizophrenia
Aetiology/Risk factors
  • Social isolation
  • Migration
  • Sensory impairment(deafness>blindness)
  • Celibacy
  • Widowhood
Very common among substance abusers (cocaine).
Associated Medical Conditions
  • Multiple sclerosis
  • Vitamin deficiency(B12 & nicotinic acid)
  • Hepatitis
  • Hypothyroidism
  • Diabetes mellitus
  • Dementia
Clinical Types
  • Somatic type
  • Persecutory type
  • Grandiose type
  • Jealous type
  • Erotomanic type
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Somatic Type
  • Also called Monosymptomatic hypochondriacal psychosis.
  • Delusions related to body.
Eg. – patient might feel that foul smell emanates from them.
That some of their body parts are mishapen(eg. nose) or non-functioning(eg. intestine).
That lice or other parasites have infested their body.
Persecutory Type
  • Most common type
  • Patient believes that he is conspired against & harassed
or bodily injured, spied or followed or poisoned by others.
  • Resentful, may resort to legal methods in order to be redressed.
OR
  • May resort to violence against his alleged persecutors.
Grandiose Type
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  • Exalted ideas about oneself, of birth, possessions & achievements.
  • In a religious context may believe that they are the chosen prophets of GOD & have mysterious powers to head the masses
Jealous Type
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  • More common in males.
  • Also called-Sexual jealousy, erotic jealousy, morbid jealousy, psychiatric jealousy, Othello syndrome.
  • Allegations of infidelity are made against the spouse supported by evidence collected in the form of changes & manner of dress, behaviour or remarks made by the partner.
  • The inferences drawn are wrong & not factual.
  • Held firmly on inadeguate grounds & are unchanged even in the face of evidence that they are false
  • Other secondary delusions may be present like he is drugged or poisoned to be put to sleep or to lose virility.
  • Mood- sadness, misery, apprehension, rage.
  • Patient resorts to spying or coercing confession from the partner often through violence that they are true.
  • Elaborate steps are taken to catch the paramour ‘red handed’ & private detectives may be engaged to watch the movements of his spouse.
  • He promises ‘to forget the whole thing & forgive them’&’not to persue the matter anymore’ once she confesses.
  • The unsuspecting wife is a bid to put an end to further turmoil ‘confesses’ which aggravates her partner’s suspicion who attempts to coerce her more with greater fervor.
  • Very resistent to treatment
  • Continues till divorce or separation or death of spouse.
  • Assaults often continued even after separation as he pleads his wife to come back and live together again.
  • Potentially dangerous & may lead to suicide or homicide.
Erotomanic Type
  • More prevalent in females.
  • Also known as- Clerambault’s Syndrome
  • Patient believes that another person, usually of a higher status or endowed with greater qualities, is loving her.
  • Persue their objects of delusion physically or through letters & presents.
  • Very often the affected woman is not attractive, hails from a poor socio-economic strata & works at a lower level job.
  • If males affected- may be violent or aggressive with the objects of love.
Clinical Features
Presence of delusion - single or a set of related delusions for atleast 3 months
  • Well systematised
  • Non-bizarre
  • Involve situations which can occur in normal life
  • ‘Encapsulated’ – they do not affect the other life spheres of the patient.
  • Hallucinations are absent.If present, are transient & rudimentary & are auditory, tactile or olfactory.
  • Only when the area of delusion is probed or confronted , the dysfunction becomes evident.
Differential diagnosis
  • Paranoid schizophrenia
  • Paranoid personality disorder
  • Substance induced delusion
  • Mood disorders
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Course & Prognosis
  • About half the cases have a chronic & unremitting course
  • In some, the symptoms occur periodically & intervals between the episodes are totally asymptomatic.
  • Suicide is often associated.
Management
  • Hospitalisation if severe impairment or suicidal/homicidal threats/ patient non- cooperative for treatment.
  • Antipsychotic + Antidepressant.
  • Antipsychotics control agitation & treat the psychotic features.
  • Drug of choice- Pimozide
  • 68% full remission, 22% partial remission.
  • Antidepressants of SSRI group such as
fluoxetine preferred.
  • Many may be refractory to treatment.
  • Electro convulsive treatment may be needed for secondary repression.
  • Psychotherapy
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